PROTAC-VHL-ligand hydrochloride ( —— )

Catalog No. M11910 CAS No. 1448189-80-7

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Product Name

PROTAC-VHL-ligand hydrochloride
Note

Research use only, not for human use.
Brief Description

PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
Description

PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
Synonyms

——
Pathway

PROTACs
Target

E3 Ligase Ligand
Recptor

Others
Research Area

——
Indication

——

CAS Number

1448189-80-7
Formula Weight

467.03
Molecular Formula

C22H31ClN4O3S
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
SMILES

CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)N)O.Cl
Chemical Name

L-Prolinamide,3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-,(4R)-, hydrochloride

1. Bondeson DP, et al. Nat Chem Biol. 2015 Aug;11(8):611-7.

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